diff --git a/src/Shentun.Peis.Application/OccupationalDiseases/OccupationalDiseaseAppService.cs b/src/Shentun.Peis.Application/OccupationalDiseases/OccupationalDiseaseAppService.cs
index c54a1d9..3784af6 100644
--- a/src/Shentun.Peis.Application/OccupationalDiseases/OccupationalDiseaseAppService.cs
+++ b/src/Shentun.Peis.Application/OccupationalDiseases/OccupationalDiseaseAppService.cs
@@ -147,6 +147,14 @@ namespace Shentun.Peis.OccupationalDiseases
             List<PatientPoison> patientPoisonList = new List<PatientPoison>();
             foreach (var item in patientPoisonsInput)
             {
+                if (patientPoisonList.Select(s => s.PoisonId).Contains(item.PoisonId))
+                {
+                    string errPoisonName = "";
+                    var errPoison = await _poisonRepository.FirstOrDefaultAsync(f => f.Id == item.PoisonId);
+                    if (errPoison != null)
+                        errPoisonName = errPoison.DisplayName;
+                    throw new UserFriendlyException($"接害因素{errPoisonName}不能重复选择");
+                }
                 patientPoisonList.Add(new PatientPoison
                 {
                     PatientRegisterId = input.PatientRegisterId,
diff --git a/src/Shentun.Peis.HttpApi.Host/PeisHttpApiHostModule.cs b/src/Shentun.Peis.HttpApi.Host/PeisHttpApiHostModule.cs
index a928ca1..da5e4b0 100644
--- a/src/Shentun.Peis.HttpApi.Host/PeisHttpApiHostModule.cs
+++ b/src/Shentun.Peis.HttpApi.Host/PeisHttpApiHostModule.cs
@@ -64,6 +64,7 @@ using Volo.Abp.BackgroundWorkers;
 using Shentun.Peis.Schedulers;
 using System.Threading.Tasks;
 using Shentun.Peis.ThirdInterfaces;
+using Microsoft.AspNetCore.Server.Kestrel.Core;
 
 namespace Shentun.Peis;
 [DependsOn(
@@ -135,14 +136,16 @@ public class PeisHttpApiHostModule : AbpModule
             opt.Password.RequiredLength = 1;
         });
 
-        ////密码策略配置
-        //context.Services.Configure<IdentityOptions>(opt =>
+
+
+        //context.Services.Configure<IISServerOptions>(opt =>
+        //{
+        //    opt.MaxRequestBodySize = 52428800;
+        //});
+
+        //context.Services.Configure<KestrelServerOptions>(opt =>
         //{
-        //    opt.Password.RequireDigit = false;
-        //    opt.Password.RequireLowercase = false;
-        //    opt.Password.RequireUppercase = false;
-        //    opt.Password.RequireNonAlphanumeric = false;
-        //    opt.Password.RequiredLength = 1;
+        //    opt.Limits.MaxRequestBodySize = 52428800;
         //});
 
         #region 临时去掉日志